Medically Reviewed by
Jason Crawford

Article Last Updated on December 26, 2022

The cannabis industry is booming, with CBD oil quickly becoming a staple on the market. Since the legalization of hemp with the 2018 Farm Bill, as the masses in the United States is quickly catching up on its beneficial properties, the interest in it is steadily increasing. The same could be said about the scientific research on CBD. Many studies have brought into light its therapeutic properties, bringing it closer to mainstream consumption.

At the same time, an array of manufacturers have appeared on the market, each offering its own range of CBD products, trying to grab the consumers’ attention. CBD oil, in particular, is now sold not only in dispensaries, but also online, in vape shops, health food and wellness stores, and even in some grocery stores.

Considering that it’s more widely available nowadays, you can come across many manufacturers on the CBD market which claim that their product is the best. But, choosing a high-quality CBD oil is imperative, and being familiar with the CBD brands that have a good reputation can help when you’re new to the CBD game.

In this article, we’ll discuss the current leading CBD oil manufacturers to help you make an informed decision and choose the best product for your needs.

What Is CBD Oil and What Are Its Benefits?

CBD (cannabidiol) is one of the major phytocannabinoids found in the cannabis plant. Along with THC (tetrahydrocannabinol), they are the key ingredients that give cannabis the characteristic properties that it’s known for. Unlike THC, which is a psychoactive compound capable of getting you high, CBD is non-intoxicating.

Even though CBD is found in all varieties of the cannabis plant, its major source is the industrial hemp plant that belongs to the Cannabis sativa L. variety. Hemp is naturally very high in CBD and low in THC, which makes it non-psychoactive. Hemp is also rich in many other cannabinoids and terpenes that work together, making it the perfect source for making CBD oil products.

CBD hemp oil is made by extracting CBD from the raw hemp plant via different methods. Some manufacturers use solvents like ethanol and butane, while others use a CO2 extraction method. The CBD hemp extract is then infused into an edible carrier oil, such as coconut oil, olive oil, and others. CBD extract can also be used to produce other CBD-infused wellness products such as capsules, tinctures, topicals (creams, balms, lotions), or edibles (candies, gummies).

CBD has many health benefits, which is why it’s an important component of medical cannabis. It’s used to help with symptoms of anxiety and depression, chronic pain relief, digestive disorders such as Crohn’s disease, as well as some forms of epilepsy. Currently, the only FDA-approved CBD product is Epidiolex, used for the treatment of two rare forms of epilepsy. 

CBD oil is well-tolerated by most people, but it can cause side effects such as nausea, digestive issues, or irritability if taken in larger quantities or if there is a sensitivity to it. Additionally, it can also react with certain medications, such as blood-thinners, so always consult with a medical professional if you’re on any meds.

CBD Oil Companies That Are Currently in the Lead

Let’s review some companies in the USA that are currently manufacturing high-quality CBD products.

CV Sciences

CV Sciences is one of the largest CBD companies in the world with 1968 retail stores as of 2019. Founded in 2010 as CannaVest, it quickly grew over the years into a successful and reliable company. CV Sciences produces high-quality hemp CBD oil and other CBD products for different market sectors such as beauty care, pet care, nutraceuticals, and functional foods. 

Elixinol Global Ltd.

Elixinol was founded in 2014 and it’s known to produce a variety of natural and organic hemp products of the highest quality. They have three divisions, each focused on different segments of the market: Elixinol Australia’s focus is medical marijuana, Hemp Foods Australia sells food products, and Elixinol USA is for dietary supplements. Elixinol USA’s selection includes full-spectrum CBD oil tinctures, soft gel capsules, topicals, and hemp seeds. They have the option of ordering a custom CBD oil blend with special formulas and different flavors.


CBDistillery is a younger company founded in 2016 in Denver, Colorado. They practice selling products of good quality for a fair price. CBDistillery sells CBD oils, CBD isolates, capsules, and creams. They extract the CBD for their products from a naturally cultivated non-GMO industrial hemp that’s THC-free. They also offer wholesale prices for their products and are tested by a third-party lab.

Charlotte’s Web

Charlotte’s Web is one of the most well-known CBD companies in the world. A family-owned business, it was founded in 2011 by seven brothers. What made them popular is their original formula that helped to open new doors towards the world of CBD. Their products are very high in CBD and very low in THC (some even have 0% THC) and apart from CBD oil, they also sell capsules, gummies, and CBD products for dogs

Canopy Growth Corporation

The Canopy Growth Corporation was formed in 2014 under the name of Tweed Marijuana and is based in Ontario, Canada. Their focus is on changing the global perception of cannabis by developing innovative products and marketing medicinal cannabis in some parts of Europe. They manufacture and distribute cannabis products through their subsidiary Bedroca. Some of their selection includes CBD oils and concentrates, capsules, and cannabis cultivars.

Aurora Cannabis

Aurora Cannabis, also based in Canada, was formed in 2016 and it has quickly become one of the biggest CBD oil manufacturers with an annual production capacity of 570.000 kg. Its primary focus is manufacturing and selling medical marijuana products, as well as THC-based products. Their CBD-based products require a prescription and these include CBD oil, gel capsules, and milled blends.

Final Thoughts

The CBD industry is booming and is becoming a large part of the cannabis market, so it’s no wonder that there are so many manufacturers trying to make it. However, only some of them have succeeded in breaking on the market and staying there for years. Some have expanded their businesses and have gained loyal customers throughout the years. And so, as CBD oil is one of the most used CBD products, being informed about companies that sell high-quality products is very important before deciding which one you’ll go for.

A passionate advocate for the benefits of cannabis. Fraser Horton, who has a background in botany and a strong love of nature, has spent years researching how cannabis affects the body and mind. He established Leaf Nation in 2020, where he has devoted himself to educating people about the legalisation of marijuana and its safe and responsible use. Fraser is committed to highlighting cannabis’ potential for improving wellness and working to dispel the stigma associated with its use.


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